What Role do Androgens Play in Endometrial Cancer?
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ABSTRACT:
SUBMITTER: Macek P
PROVIDER: S-EPMC9960114 | biostudies-literature | 2023 Feb
REPOSITORIES: biostudies-literature
Publications
What Role do Androgens Play in Endometrial Cancer?
Maček Petra P Molinari Nikolaus N Sobočan Monika M Knez Jure J
Journal of personalized medicine 20230216 2
The role of estrogens and progesterone in the development and progression of endometrial cancer is well-established, but there are very little data about the role of androgens. There are five different androgens produced in women: dehydroepiandrosterone sulphate (DHEAS), dehydroepiandrosterone (DHEA), androstenedione (A<sub>4</sub>), testosterone (T) and dihydrotestosterone (DHT). The most potent hormones are T and DHT, the latter being mainly produced from T in peripheral tissues, including end ...[more]
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