Dataset Information
Structural basis of redox modulation on chloroplast ATP synthase (reduced form)
Ontology highlight
ABSTRACT:
SUBMITTER: Po-Lin Chiu
PROVIDER: EMPIAR-10475 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
Structural basis of redox modulation on chloroplast ATP synthase.
Communications biology 20200902 1
In higher plants, chloroplast ATP synthase has a unique redox switch on its γ subunit that modulates enzyme activity to limit ATP hydrolysis at night. To understand the molecular details of the redox modulation, we used single-particle cryo-EM to determine the structures of spinach chloroplast ATP synthase in both reduced and oxidized states. The disulfide linkage of the oxidized γ subunit introduces a torsional constraint to stabilize the two β hairpin structures. Once reduced, free cysteines a ...[more]
