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CryoEM structure of EPYC1(106-135) peptide-bound Rubisco

ABSTRACT:

SUBMITTER: Hui-Ting Chou

PROVIDER: EMPIAR-10501 | biostudies-other |

REPOSITORIES: biostudies-other

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The structural basis of Rubisco phase separation in the pyrenoid.

He Shan S Chou Hui-Ting HT Matthies Doreen D Wunder Tobias T Meyer Moritz T MT Atkinson Nicky N Martinez-Sanchez Antonio A Jeffrey Philip D PD Port Sarah A SA Patena Weronika W He Guanhua G Chen Vivian K VK Hughson Frederick M FM McCormick Alistair J AJ Mueller-Cajar Oliver O Engel Benjamin D BD Yu Zhiheng Z Jonikas Martin C MC

Nature plants 20201123 12

Approximately one-third of global CO<sub>2</sub> fixation occurs in a phase-separated algal organelle called the pyrenoid. The existing data suggest that the pyrenoid forms by the phase separation of the CO<sub>2</sub>-fixing enzyme Rubisco with a linker protein; however, the molecular interactions underlying this phase separation remain unknown. Here we present the structural basis of the interactions between Rubisco and its intrinsically disordered linker protein Essential Pyrenoid Component 1 ...[more]

PMID: 33230314

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