Ontology highlight
ABSTRACT:
SUBMITTER: Sarah Victoria Barrass
PROVIDER: EMPIAR-11488 | biostudies-other |
REPOSITORIES: biostudies-other
Harder Oliver F OF Barrass Sarah V SV Drabbels Marcel M Lorenz Ulrich J UJ
Nature communications 20230913 1
Observing proteins as they perform their tasks has largely remained elusive, which has left our understanding of protein function fundamentally incomplete. To enable such observations, we have recently proposed a technique that improves the time resolution of cryo-electron microscopy (cryo-EM) to microseconds. Here, we demonstrate that microsecond time-resolved cryo-EM enables observations of fast protein dynamics. We use our approach to elucidate the mechanics of the capsid of cowpea chlorotic ...[more]