Dataset Information
Cryo-EPty SPA at CSA of 4.83 mrad
Ontology highlight
ABSTRACT:
SUBMITTER: Xudong Pei
PROVIDER: EMPIAR-11504 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
Cryogenic electron ptychographic single particle analysis with wide bandwidth information transfer.
Nature communications 20230525 1
Advances in cryogenic transmission electron microscopy have revolutionised the determination of many macromolecular structures at atomic or near-atomic resolution. This method is based on conventional defocused phase contrast imaging. However, it has limitations of weaker contrast for small biological molecules embedded in vitreous ice, in comparison with cryo-ptychography, which shows increased contrast. Here we report a single-particle analysis based on the use of ptychographic reconstruction ...[more]
