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Sodium arsenite induced gene expression changes in A549 human epithelial lung carcinoma cells

ABSTRACT: Arsenic is methylated during its metabolism, thereby depleting the intracellular methyl donor S-adenosyl-methionine, which may lead to disturbances in DNA methylation patterns which could lead to altered gene expression Cells were exposed to sodium arsenite (NaAsO2, Sigma) at concentrations of 0.08 µM, 0.4 µM and 2 µM for 1, 2 and 8 weeks.

ORGANISM(S): Homo sapiens

SUBMITTER: van Breda SG

PROVIDER: S-ECPF-GEOD-44169 | biostudies-other | 2015 Nov

REPOSITORIES: biostudies-other

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Sodium arsenite induced changes in A549 human epithelial lung carcinoma cells

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