Ontology highlight
ABSTRACT:
SUBMITTER: De Haard HJ
PROVIDER: S-EPMC1151777 | biostudies-other | 2005 Jul
REPOSITORIES: biostudies-other
De Haard Hans J W HJ Bezemer Sandra S Ledeboer Aat M AM Müller Wally H WH Boender Piet J PJ Moineau Sylvain S Coppelmans Marie-Cecile MC Verkleij Arie J AJ Frenken Leon G J LG Verrips C Theo CT
Journal of bacteriology 20050701 13
Bacteriophage p2 belongs to the most prevalent lactococcal phage group (936) responsible for considerable losses in industrial production of cheese. Immunization of a llama with bacteriophage p2 led to higher titers of neutralizing heavy-chain antibodies (i.e., devoid of light chains) than of the classical type of immunoglobulins. A panel of p2-specific single-domain antibody fragments was obtained using phage display technology, from which a group of potent neutralizing antibodies were identifi ...[more]