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Identification of low-frequency modes in protein molecules.


ABSTRACT: It is demonstrated that the observed low-frequency motions with wave numbers of 22 cm-1 and 25 cm-1 for insulin and lysozyme respectively originate from the accordion-like motions of the principal helices therein. The calculated results based on such a model are in good agreement with the observed values. During calculations the role of the internal microenvironment upon the low-frequency motion is naturally revealed, so as to elucidate as well why this kind of low-frequency motion is so sensitive to the conformations of proteins observed.

SUBMITTER: Chou KC 

PROVIDER: S-EPMC1152424 | biostudies-other | 1983 Dec

REPOSITORIES: biostudies-other

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