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Specific binding sites for 5-hydroxytryptamine on rat blood platelets.


ABSTRACT: 5-Hydroxytryptamine changes the shape of rat blood platelets by combination with a cinanserin-sensitive receptor which is not associated with the active uptake of 5-hydroxytryptamine. Binding of 5-hydroxy[3H]tryptamine to platelets at 4 degrees C demonstrates the presence of three saturable sites, and the highest-affinity site is apparently this 5-hydroxytryptamine receptor.

SUBMITTER: Drummond AH 

PROVIDER: S-EPMC1165712 | biostudies-other | 1975 Jul

REPOSITORIES: biostudies-other

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