Specificity of anti-nucleoside antibodies.
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ABSTRACT: The method of conjugation of a nucleoside or related compound to a carrier protein may have a significant effect on the specificity of the antibodies elicited. It is demonstrated, by means of the membrane-filtration assay, that anti-isopentenyladenosine antibodies produced by the ;periodate procedure' are much more reactive with the periodate-oxidized form of the nucleoside than with the parent compound. In addition, the simplicity and specificity of the assay used suggests its use as a sensitive radioimmunoassay for this multifunctional nucleoside.
SUBMITTER: Humayun MZ
PROVIDER: S-EPMC1168080 | biostudies-other | 1974 Jul
REPOSITORIES: biostudies-other
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