Ontology highlight
ABSTRACT:
SUBMITTER: Schmitt E
PROVIDER: S-EPMC1171029 | biostudies-other | 1998 Dec
REPOSITORIES: biostudies-other
The EMBO journal 19981201 23
The crystal structure of Escherichia coli methionyl-tRNAfMet transformylase complexed with formyl-methionyl-tRNAfMet was solved at 2.8 A resolution. The formylation reaction catalyzed by this enzyme irreversibly commits methionyl-tRNAfMet to initiation of translation in eubacteria. In the three-dimensional model, the methionyl-tRNAfMet formyltransferase fills in the inside of the L-shaped tRNA molecule on the D-stem side. The anticodon stem and loop are away from the protein. An enzyme loop is w ...[more]