Unknown

Dataset Information

0

Aspects of the stereochemistry of torularhodin biosynthesis.


ABSTRACT: 1. The incorporation of [2-(14)C]acetate, [2-(14)C]mevalonic acid and [2-(14)C,2-(3)H(2)]-mevalonic acid into torulene and torularhodin by Rhodotorula rubra and Rhodotorula glutinis was studied. 2. A recovery of 14.3% of the label was obtained on decarboxylation of the torularhodin biosynthesized from [2-(14)C]mevalonic acid. 3. An analysis of the (3)H/(14)C ratio in torularhodin gave a value of 9.44:8. 4. These results, obtained by different experimental techniques, show that the reactions in the conversion of the dimethyl group of isopentenyl pyrophosphate into the 16',17'-position of torularhodin must be free from randomization. A mechanism for the isomerization of isopentenyl pyrophosphate to dimethylallyl pyrophosphate is suggested.

SUBMITTER: Tefft RE 

PROVIDER: S-EPMC1179051 | biostudies-other | 1970 May

REPOSITORIES: biostudies-other

Similar Datasets

| S-EPMC1178863 | biostudies-other
| S-EPMC1184938 | biostudies-other
| S-EPMC1183844 | biostudies-other
| S-EPMC4231301 | biostudies-literature
| S-EPMC5332327 | biostudies-literature
| S-EPMC1179092 | biostudies-other
| S-EPMC3849214 | biostudies-literature
| S-EPMC1178958 | biostudies-other
| S-EPMC8234997 | biostudies-literature
| S-EPMC7414040 | biostudies-literature