Ontology highlight
ABSTRACT:
SUBMITTER: Smirnova E
PROVIDER: S-EPMC1369222 | biostudies-other | 2006 Jan
REPOSITORIES: biostudies-other
Smirnova Elena E Goldberg Elysa B EB Makarova Kira S KS Lin Lin L Brown William J WJ Jackson Catherine L CL
EMBO reports 20060101 1
Lipid droplets (LDs), also called adiposomes, are found in many eukaryotic cells, and are highly upregulated in lipid-storage cells, such as adipocytes. The mechanism by which adiposomes and their component neutral lipids are degraded is an important health issue with the rapidly spreading epidemic of obesity. Recently, a novel triglyceride lipase (adipose triglyceride lipase (ATGL)) that catalyses the initial step in triglyceride hydrolysis in adipocyte LDs was identified. Here, we show that AT ...[more]