Ontology highlight
ABSTRACT:
SUBMITTER: Mangion J
PROVIDER: S-EPMC1378085 | biostudies-other | 1999 Jul
REPOSITORIES: biostudies-other
American journal of human genetics 19990701 1
Cherubism is a rare familial disease of childhood characterized by proliferative lesions within the mandible and maxilla that lead to prominence of the lower face and an appearance reminiscent of the cherubs portrayed in Renaissance art. Resolution of these bony abnormalities is often observed after puberty. Many cases are inherited in an autosomal dominant fashion, although several cases without a family history have been reported. Using two families with clinically, radiologically, and/or hist ...[more]