Ontology highlight
ABSTRACT:
SUBMITTER: Janssen CS
PROVIDER: S-EPMC1690903 | biostudies-other | 2002 Feb
REPOSITORIES: biostudies-other
Janssen Christoph S CS Barrett Michael P MP Turner C Michael R CM Phillips R Stephen RS
Proceedings. Biological sciences 20020201 1489
A major mechanism whereby malaria parasites evade the host immune response to give chronic infections in patients' blood for months, or even years, is antigenic variation. In order to generate variant antigens, parasites require large multigene families. Although several gene families involved in these phenomena have been identified in the human malaria Plasmodium falciparum, to date no variant antigen gene families have been identified in malaria species that will infect widely used rodent labo ...[more]