Ontology highlight
ABSTRACT:
SUBMITTER: Kallinich T
PROVIDER: S-EPMC1798226 | biostudies-other | 2006 Jul
REPOSITORIES: biostudies-other
Kallinich T T Haffner D D Rudolph B B Schindler R R Canaan-Kühl S S Keitzer R R Burmester G R GR Roesen-Wolff A A Roesler J J
Annals of the rheumatic diseases 20051124 7
<h4>Background</h4>Tumour necrosis factor (TNF) receptor associated periodic syndrome (TRAPS) is caused by dominant mutations in the TNFRSF1A gene. In typical cases TRAPS begins early in childhood and is characterised by high and remittent fever over a period of 1-4 weeks or longer, accompanied by systemic and local inflammation.<h4>Case reports</h4>Patient 1 presented with recurrent episodes of weakness, migrating myalgias, arthralgias, exanthema, and chest pain lasting for 1-4 weeks, but witho ...[more]