Ontology highlight
ABSTRACT:
SUBMITTER: Haase S
PROVIDER: S-EPMC2258820 | biostudies-other | 2008 Mar
REPOSITORIES: biostudies-other
Haase Silvia S Cabrera Ana A Langer Christine C Treeck Moritz M Struck Nicole N Herrmann Susann S Jansen Pascal W PW Bruchhaus Iris I Bachmann Anna A Dias Suzana S Cowman Alan F AF Stunnenberg Hendrik G HG Spielmann Tobias T Gilberger Tim-Wolf TW
Infection and immunity 20080103 3
One of the key processes in the pathobiology of the malaria parasite is the invasion and subsequent modification of the human erythrocyte. In this complex process, an unknown number of parasite proteins are involved, some of which are leading vaccine candidates. The majority of the proteins that play pivotal roles in invasion are either stored in the apical secretory organelles or located on the surface of the merozoite, the invasive stage of the parasite. Using transcriptional and structural fe ...[more]