Ontology highlight
ABSTRACT:
SUBMITTER: Sogo LF
PROVIDER: S-EPMC2290945 | biostudies-other | 1994 Sep
REPOSITORIES: biostudies-other
The Journal of cell biology 19940901 6
Yeast cells with the mdm10 mutation possess giant spherical mitochondria and are defective for mitochondrial inheritance. The giant mitochondria display classical features of mitochondrial ultrastructure, yet they appear incapable of movement or division. Genetic analysis indicated that the mutant phenotypes resulted from a single nuclear mutation, and the isolated MDM10 gene restored wild-type mitochondrial distribution and morphology when introduced into mutant cells. MDM10 encodes a protein o ...[more]