Ontology highlight
ABSTRACT:
SUBMITTER: Baek MJ
PROVIDER: S-EPMC2375146 | biostudies-other | 2001 Oct
REPOSITORIES: biostudies-other
Baek M J MJ Kang H H Kim S E SE Park J H JH Lee J S JS Paik Y K YK Kim H H
British journal of cancer 20011001 8
Microsatellite instability (MSI) and frameshift mutations in the genes containing coding nucleotide repeats have been reported in a subset of gastric adenomas, however the inactivation profiles of DNA mismatch repair genes in MSI-positive gastric adenomas have not been characterized. To address the origin of MSI in gastric adenomas, expressions of hMLH1 and hMSH2 were explored in 86 gastric adenomas. Gastric carcinomas, of which 16 were MSI-positive and 22 MSI-negative, were used as controls. MS ...[more]