Ontology highlight
ABSTRACT:
SUBMITTER: Chang J
PROVIDER: S-EPMC2768826 | biostudies-other | 2009 Oct
REPOSITORIES: biostudies-other
Chang Jinlan J Mast Fred D FD Fagarasanu Andrei A Rachubinski Dorian A DA Eitzen Gary A GA Dacks Joel B JB Rachubinski Richard A RA
The Journal of cell biology 20091012 2
In Saccharomyces cerevisiae, peroxisomal inheritance from mother cell to bud is conducted by the class V myosin motor, Myo2p. However, homologues of S. cerevisiae Myo2p peroxisomal receptor, Inp2p, are not readily identifiable outside the Saccharomycetaceae family. Here, we demonstrate an unexpected role for Pex3 proteins in peroxisome inheritance. Both Pex3p and Pex3Bp are peroxisomal integral membrane proteins that function as peroxisomal receptors for class V myosin through direct interaction ...[more]