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Gold-catalyzed efficient synthesis of azepan-4-ones via a two-step [5 + 2] annulation.

ABSTRACT: A surprisingly efficient synthesis of azepan-4-ones via a two-step [5 + 2] annulation is developed. This reaction involves a key gold catalysis and shows generally high regioselectivities and good to excellent diastereoselectivities.

SUBMITTER: Cui L

PROVIDER: S-EPMC2867248 | biostudies-other | 2010 May

REPOSITORIES: biostudies-other

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Gold-catalyzed efficient synthesis of azepan-4-ones via a two-step [5 + 2] annulation.

Cui Li L Ye Longwu L Zhang Liming L

Chemical communications (Cambridge, England) 20100330 19

A surprisingly efficient synthesis of azepan-4-ones via a two-step [5 + 2] annulation is developed. This reaction involves a key gold catalysis and shows generally high regioselectivities and good to excellent diastereoselectivities. ...[more]

PMID: 20442898

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