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Emerging concepts in acute kidney injury following cardiac surgery.


ABSTRACT: Acute kidney injury (AKI) remains a significant cause of morbidity and mortality following cardiac surgery. Through a more thorough understanding of perioperative genomics and the evolving role of early biomarkers of AKI, the authors seek to improve meaningful outcomes among cardiac surgery patients. In this review, the focus will be on advances in risk stratification, evolving definitions and improving early diagnosis of AKI, identification of effective individualized therapies, and future directions.

SUBMITTER: Hudson C 

PROVIDER: S-EPMC2908719 | biostudies-other | 2008 Dec

REPOSITORIES: biostudies-other

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Emerging concepts in acute kidney injury following cardiac surgery.

Hudson Christopher C   Hudson Jordan J   Swaminathan Madhav M   Shaw Andrew A   Stafford-Smith Mark M   Patel Uptal D UD  

Seminars in cardiothoracic and vascular anesthesia 20081119 4


Acute kidney injury (AKI) remains a significant cause of morbidity and mortality following cardiac surgery. Through a more thorough understanding of perioperative genomics and the evolving role of early biomarkers of AKI, the authors seek to improve meaningful outcomes among cardiac surgery patients. In this review, the focus will be on advances in risk stratification, evolving definitions and improving early diagnosis of AKI, identification of effective individualized therapies, and future dire  ...[more]

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