Ontology highlight
ABSTRACT:
SUBMITTER: Sasaki S
PROVIDER: S-EPMC294077 | biostudies-other | 1994 Mar
REPOSITORIES: biostudies-other
Sasaki S S Fushimi K K Saito H H Saito F F Uchida S S Ishibashi K K Kuwahara M M Ikeuchi T T Inui K K Nakajima K K
The Journal of clinical investigation 19940301 3
We recently cloned a cDNA of the collecting duct apical membrane water channel of rat kidney, which is important for the formation of concentrated urine (Fushima, K., S. Uchida, Y. Hara, Y. Hirata, F. Marumo, and S. Sasaki. 1993. Nature [Lond.]. 361:549-552). Since urine concentrating ability varies among mammalian species, we examined whether an homologous protein is present in human kidney. By screening a human kidney cDNA library, we isolated a cDNA clone, designated human aquaporin of collec ...[more]