3,5-Bis(ethoxy-carbon-yl)-2,6-dimethyl-1,4-dihydro-pyridine-4-carboxylic acid.

ABSTRACT: The title mol-ecule, C(14)H(19)NO(6), was synthesized by the reaction of glyoxylic acid, ethyl acetoacetate and NH(4)HCO(3). In the crystal structure, the dihydro-pyridine ring adopts an asymmetric boat-type conformation with the C atom bearing the carboxyl group showing a signficantly larger deviation [0.325?(2)?Å] from the base plane then the N atom [0.137?(2)?Å]. One of the ethyl groups is disordered over two positions with occupancies of 0.741?(10) and 0.259?(10). The crystal is stabilized by strong inter-molecular hydrogen bonds. N-H?O inter-actions form infinite chains in the a direction. O-H?O hydrogen bonds form typical carboxylic acid dimers, which link the N-H?O chains into a ladder-type double chain.

SUBMITTER: Wu DH 

PROVIDER: S-EPMC2977273 | biostudies-other | 2009

REPOSITORIES: biostudies-other