Ontology highlight
ABSTRACT:
SUBMITTER: Hermanson GG
PROVIDER: S-EPMC298057 | biostudies-other | 1989 Oct
REPOSITORIES: biostudies-other
Hermanson G G GG Briskin M M Sigman D D Wall R R
Proceedings of the National Academy of Sciences of the United States of America 19891001 19
B29 is a B-cell-specific member of the immunoglobulin gene superfamily that is expressed throughout B-cell development beginning with the earliest precursor B cells undergoing immunoglobulin heavy-chain gene segment rearrangements. We have analyzed the region upstream of the B29 gene to identify DNA sequences involved in transcriptional regulation of this gene. The B29 gene lacks a TATA box and transcription is initiated at multiple sites. The B29 gene sequence 5' of these transcription start si ...[more]