Ontology highlight
ABSTRACT:
SUBMITTER: Olins AL
PROVIDER: S-EPMC3104809 | biostudies-other | 2011 Jan-Feb
REPOSITORIES: biostudies-other
Olins Ada L AL Langhans Markus M Monestier Marc M Schlotterer Andreas A Robinson David G DG Viotti Corrado C Zentgraf Hanswalter H Zwerger Monika M Olins Donald E DE
Nucleus (Austin, Tex.) 20110101 1
Interphase nuclear architecture is disrupted and rapidly reformed with each cell division cycle. Successive cell generations exhibit a "memory" of this nuclear architecture, as well as for gene expression. Furthermore, many features of nuclear and mitotic chromosome structure are recognizably species and tissue specific. We wish to know what properties of the underlying chromatin structure may determine these conserved features of nuclear architecture. Employing a particular mouse autoimmune ant ...[more]