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3-(4-Chloro-benzo-yl)-4-(4-chloro-phen-yl)-1-phenethyl-piperidin-4-ol.

ABSTRACT: In the title compound, C(26)H(25)Cl(2)NO(2), the piperidine ring adopts a chair conformation with a cis configuration of the carbonyl and hy-droxy substituents. The dihedral angle between the aromatic rings of the chloro-benzene groups is 24.3?(2)°. The phenyl ring forms dihedral angles of 59.4?(3) and 44.1?(3)° with the benzene rings. In the crystal, mol-ecules are linked by inter-molecular O-H?N and C-H?O hydrogen bonds and C-H?? inter-actions into layers parallel to the bc plane.

SUBMITTER: Ayd?n A

PROVIDER: S-EPMC3120371 | biostudies-other | 2011 Jun

REPOSITORIES: biostudies-other

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3-(4-Chloro-benzo-yl)-4-(4-chloro-phen-yl)-1-phenethyl-piperidin-4-ol.

Aydın Abdullah A Akkurt Mehmet M Mete Ebru E Sahin Ertan E Gul Halise Inci HI

Acta crystallographica. Section E, Structure reports online 20110520 Pt 6

In the title compound, C(26)H(25)Cl(2)NO(2), the piperidine ring adopts a chair conformation with a cis configuration of the carbonyl and hy-droxy substituents. The dihedral angle between the aromatic rings of the chloro-benzene groups is 24.3 (2)°. The phenyl ring forms dihedral angles of 59.4 (3) and 44.1 (3)° with the benzene rings. In the crystal, mol-ecules are linked by inter-molecular O-H⋯N and C-H⋯O hydrogen bonds and C-H⋯π inter-actions into layers parallel to the bc plane. ...[more]

PMID: 21754823

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