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4-(4-Chloro-phen-yl)piperidin-4-ol.

ABSTRACT: In the title compound, C(11)H(14)ClNO, the piperidine ring adopts a chair conformation: the hydroxyl substituent and the N-bound H atom occupy the axial positions, while the benzene ring occupies the equatorial position. In the crystal, the mol-ecules are linked into a centrosymmetric tetra-mer through strong O-H?N and weak N-H?O hydrogen bonds; the N and O atoms act as both donor and acceptor for these inter-actions. The tetra-mers are further joined by hydrogen bonds into a layer parallel to (100).

SUBMITTER: Dutkiewicz G

PROVIDER: S-EPMC2983646 | biostudies-literature | 2010 Feb

REPOSITORIES: biostudies-literature

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4-(4-Chloro-phen-yl)piperidin-4-ol.

Dutkiewicz Grzegorz G Siddaraju B P BP Yathirajan H S HS Siddegowda M S MS Kubicki Maciej M

Acta crystallographica. Section E, Structure reports online 20100206 Pt 3

In the title compound, C(11)H(14)ClNO, the piperidine ring adopts a chair conformation: the hydroxyl substituent and the N-bound H atom occupy the axial positions, while the benzene ring occupies the equatorial position. In the crystal, the mol-ecules are linked into a centrosymmetric tetra-mer through strong O-H⋯N and weak N-H⋯O hydrogen bonds; the N and O atoms act as both donor and acceptor for these inter-actions. The tetra-mers are further joined by hydrogen bonds into a layer parallel to ( ...[more]

PMID: 21580330

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