Ontology highlight
ABSTRACT:
SUBMITTER: Pallaoro A
PROVIDER: S-EPMC3189017 | biostudies-other | 2011 Oct
REPOSITORIES: biostudies-other
Proceedings of the National Academy of Sciences of the United States of America 20110919 40
A multiplexed, ratiometric method is described that can confidently distinguish between cancerous and noncancerous epithelial prostate cells in vitro. The technique is based on bright surface-enhanced resonance Raman scattering (SERRS) biotags (SBTs) infused with unique Raman reporter molecules, and carrying cell-specific peptides. Two sets of SBTs were used. One targets the neuropilin-1 (NRP-1) receptors of cancer cells through the RPARPAR peptide. The other functions as a positive control (PC) ...[more]