Dataset Information
"Clickable", polymerized liposomes as a versatile and stable platform for rapid optimization of their peripheral compositions.
Ontology highlight
ABSTRACT:
SUBMITTER: Kumar A
PROVIDER: S-EPMC3235329 | biostudies-other | 2010 Aug
REPOSITORIES: biostudies-other
Publications
"Clickable", polymerized liposomes as a versatile and stable platform for rapid optimization of their peripheral compositions.
Chemical communications (Cambridge, England) 20100628 31
A versatile and stable liposomal platform is developed for rapid optimization of its peripheral composition. The platform is based on polydiacetylene lipids terminated with alkynyl groups. Conditions for copper-catalyzed azide-alkyne cycloaddition (a "click" reaction) are optimized for rapid attachment of azides with controlled composition onto the liposomes. ...[more]