Ontology highlight
ABSTRACT:
SUBMITTER: Bianconi A
PROVIDER: S-EPMC3285732 | biostudies-other | 2012 Jan
REPOSITORIES: biostudies-other
Bianconi Antonio A Ciasca Gabriele G Tenenbaum Alexander A Battisti Anna A Campi Gaetano G
Journal of biological physics 20111116 1
We report the variation with temperature of the ensemble distribution of conformations spanned by the tau protein in its dynamical states measured by small-angle X-ray scattering (SAXS) using synchrotron radiation. The SAXS data show a clear temperature variation of the distribution of occupied protein conformations from 293 to 318 K. More conformations with a smaller radius of gyration are occupied at higher temperature. The protein-solvent interactions are shown by computer simulation to be es ...[more]