Ontology highlight
ABSTRACT:
SUBMITTER: Shibuya H
PROVIDER: S-EPMC331067 | biostudies-other | 1990 Jul
REPOSITORIES: biostudies-other
Shibuya H H Yoneyama M M Nakamura Y Y Harada H H Hatakeyama M M Minamoto S S Kono T T Doi T T White R R Taniguchi T T
Nucleic acids research 19900701 13
The chromosomal gene for the human interleukin-2 receptor beta-chain (IL-2R beta) was isolated and characterized. The entire IL-2R beta gene is composed of ten exons spanning about 24.3 kilobases, in which the protein is encoded by the exons 2-10. The cysteine rich extracellular region which displays a significant evolutionary resemblance to other cytokine receptors, as well as growth hormone and prolactin receptors, is encoded primarily by exons 3 and 4, whereas the membrane proximal, cysteine ...[more]