Ontology highlight
ABSTRACT:
SUBMITTER: Lin Z
PROVIDER: S-EPMC3321928 | biostudies-other | 2011
REPOSITORIES: biostudies-other
Progress in molecular biology and translational science 20110101
Transporters of dopamine, serotonin, and norepinephrine have been empirically used as medication targets for several mental illnesses in the last decades. These protein-targeted medications are effective only for subpopulations of patients with transporter-related brain disorders. Since the cDNA clonings in early 1990s, molecular studies of these transporters have revealed a wealth of information about the transporters' structure-activity relationship (SAR), neuropharmacology, cell biology, bioc ...[more]