Ontology highlight
ABSTRACT:
SUBMITTER: Saint-Hubert MD
PROVIDER: S-EPMC3478112 | biostudies-other | 2012
REPOSITORIES: biostudies-other
Saint-Hubert Marijke De MD Brepoels Lieselot L Devos Ellen E Vermaelen Peter P Groot Tjibe De TD Tousseyn Thomas T Mortelmans Luc L Mottaghy Felix M FM
American journal of nuclear medicine and molecular imaging 20111215 1
<h4>Purpose</h4>Evaluation and comparison of 3'-[(18)F]-fluoro-3'-deoxy-L-thymidine (FLT) and 2-[(18)F]-fluoro-2-deoxyglucose (FDG)-PET to monitor early response following both cyclophosphamide and temsirolimus treatment in a mouse model of Burkitt lymphoma.<h4>Methods</h4>Daudi xenograft mice were treated with either cyclophosphamide or temsirolimus and imaged with FLT-PET and FDG-PET on appropriate days post therapy inititiation. Immunohistochemical (IHC) studies (H&E, TUNEL, CD20, PCNA and ki ...[more]