"Aligned-to-random" nanofiber scaffolds for mimicking the structure of the tendon-to-bone insertion site.
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ABSTRACT:
SUBMITTER: Xie J
PROVIDER: S-EPMC3609028 | biostudies-other | 2010 Jun
REPOSITORIES: biostudies-other
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"Aligned-to-random" nanofiber scaffolds for mimicking the structure of the tendon-to-bone insertion site.
Xie Jingwei J Li Xiaoran X Lipner Justin J Manning Cionne N CN Schwartz Annie G AG Thomopoulos Stavros S Xia Younan Y
Nanoscale 20100511 6
We have demonstrated the fabrication of "aligned-to-random" electrospun nanofiber scaffolds that mimic the structural organization of collagen fibers at the tendon-to-bone insertion site. Tendon fibroblasts cultured on such a scaffold exhibited highly organized and haphazardly oriented morphologies, respectively, on the aligned and random portions. ...[more]
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