Ontology highlight
ABSTRACT:
SUBMITTER: Rodriguez-Perez N
PROVIDER: S-EPMC3850619 | biostudies-other | 2008
REPOSITORIES: biostudies-other
Rodríguez-Pérez N N Aguinaga-Barrilero A A Gorroño-Echebarría Marina B MB Pérez-Blas Mercedes M Martín-Villa J M JM
Disease markers 20080101 2
We wished to analyse the frequency of Crohn's disease-linked CARD15 polymorphisms (P268S, R702W, G908R and 1007fs) in a group of Spanish patients with idiopathic uveitis. To this aim, DNA samples were obtained from 111 unrelated patients. P268S, R702W and G908R polymorphisms were detected using TaqMan Genotyping kits (Applied Biosystems), and the 1007fs variation by direct DNA sequencing. Control group consisted of 105 healthy subjects. None of the polymorphisms studied revealed a significant in ...[more]