Ontology highlight
ABSTRACT:
SUBMITTER: Wicky C
PROVIDER: S-EPMC38581 | biostudies-other | 1996 Aug
REPOSITORIES: biostudies-other
Wicky C C Villeneuve A M AM Lauper N N Codourey L L Tobler H H Müller F F
Proceedings of the National Academy of Sciences of the United States of America 19960801 17
Telomeres are specialized structures located at the ends of linear eukaryotic chromosomes that ensure their complete replication and protect them from fusion and degradation. We report here the characterization of the telomeres of the nematode Caenorhabditis elegans. We show that the chromosomes terminate in 4-9 kb of tandem repeats of the sequence TTAGGC. Furthermore, we have isolated clones corresponding to 11 of the 12 C. elegans telomeres. Their subtelomeric sequences are all different from ...[more]