Ontology highlight
ABSTRACT:
SUBMITTER: Liu N
PROVIDER: S-EPMC3964114 | biostudies-other | 2014 Mar
REPOSITORIES: biostudies-other
Liu Ning N Nelson Benjamin R BR Bezprozvannaya Svetlana S Shelton John M JM Richardson James A JA Bassel-Duby Rhonda R Olson Eric N EN
Proceedings of the National Academy of Sciences of the United States of America 20140303 11
Regeneration of adult skeletal muscle following injury occurs through the activation of satellite cells, an injury-sensitive muscle stem cell population that proliferates, differentiates, and fuses with injured myofibers. Members of the myocyte enhancer factor 2 (MEF2) family of transcription factors play essential roles in muscle differentiation during embryogenesis, but their potential contributions to adult muscle regeneration have not been systematically explored. To investigate the potentia ...[more]