A new player in Pol II pausing.
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ABSTRACT: Transcriptional control plays a primary role in gene expression and can be exerted at multiple levels of the transcription process, such as RNA polymerase recruitment and promoter-proximal pausing. A recent report published in The EMBO Journal (Li and Gilmour, 2013) provides new insights into the regulation of a large class of paused genes through the identification of a novel transcription factor (TF; Motif 1 binding protein, M1BP) that binds to promoters of paused genes and controls their expression.
SUBMITTER: Fuda NJ
PROVIDER: S-EPMC3981171 | biostudies-other | 2013 Jul
REPOSITORIES: biostudies-other
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