Ontology highlight
ABSTRACT:
SUBMITTER: Sutherland JD
PROVIDER: S-EPMC41267 | biostudies-other | 1995 Aug
REPOSITORIES: biostudies-other
Proceedings of the National Academy of Sciences of the United States of America 19950801 17
In Drosophila the response to the hormone ecdysone is mediated in part by Ultraspiracle (USP) and ecdysone receptor (EcR), which are members of the nuclear receptor superfamily. Heterodimers of these proteins bind to ecdysone response elements (EcREs) and ecdysone to modulate transcription. Herein we describe Drosophila hormone receptor 38 (DHR38) and Bombyx hormone receptor 38 (BHR38), two insect homologues of rat nerve growth factor-induced protein B (NGFI-B). Although members of the NGFI-B fa ...[more]