Fitness cost of SCCmec and methicillin resistance levels in Staphylococcus aureus.

ABSTRACT: Transformation of a type I SCCmec element into Staphylococcus aureus yielded highly oxacillin-resistant transformants with a reduced growth rate. Faster-growing variants could again be selected at the cost of reduced resistance levels, demonstrating an inverse correlation between oxacillin resistance levels and growth rate.

SUBMITTER: Ender M 

PROVIDER: S-EPMC415608 | biostudies-other | 2004 Jun

REPOSITORIES: biostudies-other