Ontology highlight
ABSTRACT:
SUBMITTER: Taylor JN
PROVIDER: S-EPMC4361849 | biostudies-other | 2015
REPOSITORIES: biostudies-other
Scientific reports 20150317
Characterization of states, the essential components of the underlying energy landscapes, is one of the most intriguing subjects in single-molecule (SM) experiments due to the existence of noise inherent to the measurements. Here we present a method to extract the underlying state sequences from experimental SM time-series. Taking into account empirical error and the finite sampling of the time-series, the method extracts a steady-state network which provides an approximation of the underlying e ...[more]