Ontology highlight
ABSTRACT:
SUBMITTER: Egami H
PROVIDER: S-EPMC4600224 | biostudies-other | 2015 Oct
REPOSITORIES: biostudies-other
Chemistry, an Asian journal 20150616 10
Hydrotrifluoromethylation, vinylic trifluoromethylation, and iodotrifluoromethylation of simple alkenes have been achieved by using Togni reagent in the absence of any transition metal catalyst. These reactions were readily controllable by selection of appropriate salts and solvents. The addition of K2CO3 afforded the hydrotrifluoromethylation product, with DMF acting not only as a solvent, but also as the hydrogen source. In contrast, the use of tetra-n-butylammonium iodide (TBAI) in 1,4-dioxan ...[more]