Histone acetylation: novel target for the treatment of acute lymphoblastic leukemia.
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ABSTRACT:
SUBMITTER: Zhang C
PROVIDER: S-EPMC4634719 | biostudies-other | 2015
REPOSITORIES: biostudies-other
Publications
Histone acetylation: novel target for the treatment of acute lymphoblastic leukemia.
Zhang Cheng C Zhong Jiang F JF Stucky Andres A Chen Xue-Lian XL Press Michael F MF Zhang Xi X
Clinical epigenetics 20151104
Acute lymphoblastic leukemia (ALL) has been generally considered a genetic disease (disorder) with an aggressive tumor entity of highly proliferative malignant lymphoid cells. However, in recent years, significant advances have been made in the elucidation of the ALL-associated processes. Thus, we understand that histone acetylation is involved in the permanent changes of gene expression controlling ALL developmental outcomes. In this article, we will focus on histone acetylation associated with ...[more]
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