Ontology highlight
ABSTRACT:
SUBMITTER: Nguyen CM
PROVIDER: S-EPMC4679559 | biostudies-other | 2015 Nov
REPOSITORIES: biostudies-other
Journal of dermatological science 20150824 2
Genomic imprinting is a genetic process where only one allele of a particular gene is expressed in a parent-of-origin dependent manner. Epigenetic changes in the DNA, such as methylation or acetylation of histones, are primarily thought to be responsible for silencing of the imprinted allele. Recently, global CpG methylation changes have been identified in psoriatic skin in comparison to normal skin, particularly near genes known to be upregulated in psoriasis such as KYNU, OAS2, and SERPINB3. F ...[more]