Unknown

Dataset Information

0

Lactic acid polarizes macrophages to a tumor-promoting state.


ABSTRACT: Tumor-associated macrophages have been associated with a poor prognosis in most types of tumors. However, tumor-derived signals that activate macrophages have not been well defined. We review our recent finding that tumor-derived lactic acid is necessary and sufficient to polarize tumor-associated macrophages to a tumor-promoting state.

SUBMITTER: Colegio OR 

PROVIDER: S-EPMC4839384 | biostudies-other | 2016 Mar

REPOSITORIES: biostudies-other

Similar Datasets

| S-EPMC4040301 | biostudies-literature
| PRJNA833940 | ENA
| PRJNA435410 | ENA
| PRJNA311720 | ENA
| PRJNA816552 | ENA
| S-EPMC3582771 | biostudies-literature
2020-10-01 | GSE158801 | GEO
| S-SCDT-EMM-2019-11210 | biostudies-other
| S-EPMC8080575 | biostudies-literature
| S-EPMC7539200 | biostudies-literature