Ontology highlight
ABSTRACT:
SUBMITTER: Zou K
PROVIDER: S-EPMC4847808 | biostudies-other | 2016
REPOSITORIES: biostudies-other
Cancer biology & therapy 20160101 1
Members of krüppel-like factor family have been shown to play critical roles in the development, metabolism and tumorigenesis. Our previous study demonstrated that up-regulationupregulation of KLF2 in livers from obese mice could promote hepatosteatosis. However, little is known about its effects in hepatocellular carcinogenesis. In the present study, we found that mRNA and protein expression of KLF2 was increased in primary HCC, when compared with that in adjacent normal liver. In vitro studies ...[more]