Ontology highlight
ABSTRACT:
SUBMITTER: Li W
PROVIDER: S-EPMC4965746 | biostudies-other | 2016
REPOSITORIES: biostudies-other
Li Wei W Zhao Xiaoxu X Du Bin B Li Xin X Liu Shuhao S Yang Xiao-Yan XY Ding Hui H Yang Wende W Pan Fan F Wu Xiaobo X Qin Li L Pan Yunlong Y
Scientific reports 20160729
Tumour vasculature is generally disordered because of the production of excessive angiogenic factors by tumour cells, which results in tumour progression and reduces the effectiveness of radiotherapy or chemotherapy. Transient anti-angiogenic therapies that regulate tumour vascular morphology and function and improve the efficiency of antitumour therapy are under investigation. Recombinant human endostatin (Endostar/rhES) is a vascular angiogenesis-disrupting agent that has been used to treat no ...[more]