Ontology highlight
ABSTRACT:
SUBMITTER: Obradovic H
PROVIDER: S-EPMC5155103 | biostudies-other | 2016
REPOSITORIES: biostudies-other
Obradović Hristina H Krstić Jelena J Kukolj Tamara T Trivanović Drenka D Đorđević Ivana Okić IO Mojsilović Slavko S Jauković Aleksandra A Jovčić Gordana G Bugarski Diana D Santibañez Juan Francisco JF
Mediators of inflammation 20161130
Interleukin 17 (IL-17) is a cytokine with pleiotropic effects associated with several inflammatory diseases. Although elevated levels of IL-17 have been described in inflammatory myopathies, its role in muscle remodeling and regeneration is still unknown. Excessive extracellular matrix degradation in skeletal muscle is an important pathological consequence of many diseases involving muscle wasting. In this study, the role of IL-17 on the expression of matrix metalloproteinase- (MMP-) 9 in myobla ...[more]