Ontology highlight
ABSTRACT:
SUBMITTER: El Assal R
PROVIDER: S-EPMC5177905 | biostudies-other | 2016 Dec
REPOSITORIES: biostudies-other
El Assal Rami R Gurkan Umut A UA Chen Pu P Juillard Franceline F Tocchio Alessandro A Chinnasamy Thiruppathiraja T Beauchemin Chantal C Unluisler Sebnem S Canikyan Serli S Holman Alyssa A Srivatsa Srikar S Kaye Kenneth M KM Demirci Utkan U
Scientific reports 20161222
Cancer cells have been increasingly grown in pharmaceutical research to understand tumorigenesis and develop new therapeutic drugs. Currently, cells are typically grown using two-dimensional (2-D) cell culture approaches, where the native tumor microenvironment is difficult to recapitulate. Thus, one of the main obstacles in oncology is the lack of proper infection models that recount main features present in tumors. In recent years, microtechnology-based platforms have been employed to generate ...[more]